Nortriptyline

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    Product name: Nortriptyline
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    Generic name: Nortriptyline
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    Dosage form: Oral tablets
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    Packaging: Box of 5 blisters of 20 F.C. tablets.
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    Drug Category: Neurology and Psychiatry

Indications:

Treatment of symptoms of depression.
Relief of nocturnal enuresis in some patients over the age of six years.

Dosage and Administration:

Adults: 1 x 25mg up to three times daily, increasing stepwise to 150-200mg. This should be reached by the end of the first week and maintained until definite improvement has occurred. The subsequent maintenance dose should be individually determined by gradually reducing the dosage, usually to about 50-100mg daily. 
In patients in hospital, i.e. severe cases, the dose may be increased to 100mg three times daily until a distinct improvement is seen. Again the subsequent maintenance dose should be determined individually by reducing the dosage, usually to about 100mg daily. 
Geriatric: Patients over 60 years may respond to lower doses of imipramine than those recommended above. Treatment should be initiated with 10mg daily, gradually increasing to 30-50mg daily. The optimum dose should be reached after about 10 days and then continued until the end of treatment. 
Pediatric (for nocturnal enuresis only): The tablets should be administered just before bedtime. 

Contraindication:

Hypersensitivity to nortriptyline or to any of the excipients.
Recent myocardial infarction, any degree of heart block or other cardiac arrhythmias.
Severe liver disease.
Mania.
Nortriptyline is contra-indicated for the nursing mother and for children under the age of six years.